SM412F CD11a / ITGAL (+ CD18) antibody

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Rat anti Canine CD11a / ITGAL YKIX490.6.4


Product Description for CD11a / ITGAL

Rat anti Canine CD11a / ITGAL YKIX490.6.4.
Properties: (+ CD18)
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for CD11a / ITGAL

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CD11 antigen-like family member A, CD11a, CD18, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
Presentation FITC
Reactivity Can
Applications F
Clonality Monoclonal
Clone YKIX490.6.4
Host Rat
Isotype IgG2c
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Canine thymocytes. Spleen cells from immunised DA rat were fused with cells of the Y3/A1.2.3 rat myeloma cell line.
Property + CD18
Application Flow Cytometry: Neat - 1/5; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Background The antigen is expressed by most leucocytes, although expression on peripheral blood lymphocytes is weak.
Concentration 0.1 mg/ml
General Readings
  1. Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994 Mar;43(3):137-54. PubMed PMID: 8091414.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Fluorescein Isothiocyanate Isomer 1
Affinity chromatography on Protein G
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Liquid purified IgG
This antibody has been assigned to the CD11/18 group, recognising a cell surface antigen of 90/180kD. Clone YKIX 490.6.4 is reported to block T-cell proliferation, CTL and ADCC killing and homotypic adhesion.

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