SM412P CD11a / ITGAL (+ CD18) antibody

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Rat anti Canine CD11a / ITGAL YKIX490.6.4


Product Description for CD11a / ITGAL

Rat anti Canine CD11a / ITGAL YKIX490.6.4.
Properties: (+ CD18)
Presentation: Purified
Product is tested for Immunoprecipitation, Flow Cytometry.

Properties for CD11a / ITGAL

Product Category Primary Antibodies
Quantity 0.25 mg
Synonyms CD11 antigen-like family member A, CD11a, CD18, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
Presentation Purified
Reactivity Can
Applications F, IP
Clonality Monoclonal
Clone YKIX490.6.4
Host Rat
Isotype IgG2c
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Canine thymocytes. Spleen cells from DA rats were fused with cells of the rat Y3/Ag1.2.3 myeloma cell line.
Property + CD18
Application Immunoprecipitation.
Flow Cytometry: 1/50 - 1/100; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Background The antigen is expressed by most leucocytes, although expression on peripheral blood lymphocytes is weak.
Concentration 1.0 mg/ml
General Readings
  1. Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994 Mar;43(3):137-54. PubMed PMID: 8091414.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity chromatography on Protein G
Buffer System:
PBS containing 0.09% Sodium Azide
Liquid purified IgG
This antibody has been assigned to the CD11/18 group, recognising a leukocyte cell adhesion molecule (LeuCAM) composed of the 180kDa CD11a chain complexed with the 95kDa common beta chain CD18cell. The antibody blocks T cell proliferation, CTL and ADCC killing, and homotypic adhesion.
Canine (Dog).

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