discontinued

VBAQ153-01 CD11c / ITGAX antibody

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0.1 mg / €130.00

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Mouse anti Bovine, Goat, Sheep CD11c / ITGAX BAQ153A

VBAQ153-01

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  • VBAQ153-01

Product Description for CD11c / ITGAX

Mouse anti Bovine, Goat, Sheep CD11c / ITGAX BAQ153A.
Presentation: Ascites
Product is tested for Frozen Sections, Flow Cytometry.

Properties for CD11c / ITGAX

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms 95, 95 alpha chain, CD11 antigen-like family member C, CD11c, ITGAX, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150
Presentation Ascites
Reactivity Bov, Gt, Sh
Applications C, F
Clonality Monoclonal
Clone BAQ153A
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer VMRD Inc.

Datasheet Extract

Application Flow cytometry.
Immunohistochemistry.
Cell function assays.
Background CD11c expression is high on monocytes, macrophages and NK cells, moderate on granulocytes, and least on subsets of T and B cells. The level of expression on granulocytes can vary from low to high. Expression is low in sheep and rabbits, and moderate in cattle. The level of expression increases on B cells in B lymphocytotic cattle infected with bovine leukemia virus. It is also expressed on lymphoid cell lines including hairy cell leukemias in humans.
Concentration 1.0 mg/ml
General Readings
  1. Howard CJ, Morrison WI, Bensaid A, Davis W, Eskra L, Gerdes J, et al. Summary of workshop findings for leukocyte antigens of cattle. Vet Immunol Immunopathol. 1991 Jan;27(1-3):21-7. PubMed PMID: 1902342.
  2. Stone DM, Norton LK, Davis WC. Modulation of bovine leukemia virus-associated spontaneous lymphocyte proliferation by monoclonal antibodies to lymphocyte surface molecules. Clin Immunol Immunopathol. 1997 May;83(2):156-64. PubMed PMID: 9143376.
  3. Sager H, Davis WC, Dobbelaere DA, Jungi TW. Macrophage-parasite relationship in theileriosis. Reversible phenotypic and functional dedifferentiation of macrophages infected with Theileria annulata. J Leukoc Biol. 1997 Apr;61(4):459-68. PubMed PMID: 9103233.
  4. Pighetti GM, Sordillo LM. Specific immune responses of dairy cattle after primary inoculation with recombinant bovine interferon-gamma as an adjuvant when vaccinating against mastitis. Am J Vet Res. 1996 Jun;57(6):819-24. PubMed PMID: 8725806.
  5. Herrmann LM, Cheevers WP, Davis WC, Knowles DP, O'Rourke KI. CD21-positive follicular dendritic cells: A possible source of PrPSc in lymph node macrophages of scrapie-infected sheep. Am J Pathol. 2003 Apr;162(4):1075-81. PubMed PMID: 12651600. (Free PMC Article available, 5 images available)
  6. Harbo SJ, Barrington GM, Allen AJ, Sample GL, Parish SM, Hamilton MJ, et al. Characterization of lymphocyte populations by flow cytometry in a calf with sporadic juvenile lymphoma. Vet Clin Pathol. 2004;33(3):163-7. PubMed PMID: 15334353.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Clarified by centrifugation, and filtered through a 0.2 μM filter.
Buffer System:
Phosphate-buffered saline containing 0.09% sodium azide
State:
Liquid ascites fluid
Ascites
Species Reactivity
Species reactivity (expected):
Water buffalo, Cape buffalo, Big horn sheep, White tail deer, Mule deer, Black tail deer, Elk, Bison.
Species reactivity (tested):
Bovine, Goat, Sheep. Does not react with llama or camel.
Specificity
Specificity:
Labels 54 % PBMC and 100 % granulocytes.

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