AM26341PU-N CD121a / IL1R1 antibody

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0.1 mg / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse CD121a / IL1R1 REG21

AM26341PU-N

Product Description for CD121a / IL1R1

Rat anti Mouse CD121a / IL1R1 REG21.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Immunoprecipitation, Enzyme Immunoassay, Functional assay.

Properties for CD121a / IL1R1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms IL-1R-alpha, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I
Presentation Purified
Reactivity Ms
Applications E, FN, IP, WB
Clonality Monoclonal
Clone REG21
Host Rat
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P13504
GeneID:
16177
Isotype control SM25P, SM25PX
Application Functional assays (Inhibition in biological assays, in vitro as well as in vivo).
Immunoassays.
Immunoprecipitation.
Western blot: The typical starting working dilution is 1:10.
Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.
Background The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
Concentration 0.1 mg/ml
General Readings
  1. Kojouharoff G, Hans W, Obermeier F, Männel DN, Andus T, Schölmerich J, et al. Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice. Clin Exp Immunol. 1997 Feb;107(2):353-8. PubMed PMID: 9030875. (Free PMC Article available)
  2. Stern AS, Pan YC, Hellmann RS, Parker KP, Mueller D, Hulmes JD, et al. Purification of homogeneity and amino acid sequence analysis of a receptor protein for interleukin 1. Arch Biochem Biophys. 1989 Oct;274(1):26-36. PubMed PMID: 2528328.
Storage

Store at 2 - 8 °C.
Shelf life: one year from despatch.

Format
Purification:
Protein G
Buffer System:
PBS
Preservatives:
0.02% sodium azide
Stabilizers:
0.1% bovine serum albumin
State:
Liquid 0.2 µm filtered Ig fraction
Purified
Specificity
Specificity:
The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I.
Species:
Mouse.

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