AP18112PU-N CD146 antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human CD146

Product Description for CD146

Rabbit anti Human CD146.
Product is tested for Western blot / Immunoblot.

Properties for CD146

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P43121
Immunogen:
KLH conjugated synthetic peptide selected from the Center region of human MCAM
GeneID:
4162
Application ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Background MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Concentration lot specific
General Readings
  1. Fritzsche,F.R., Pathology 40 (5), 457-464 (2008)
  2. Malyszko,J., Clin. Appl. Thromb. Hemost. 14 (3), 338-345 (2008)
  3. Guezguez,B., J. Immunol. 179 (10), 6673-6685 (2007)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Saturated Ammonium Sulfate (SAS) precipitation
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Specificity
Specificity:
This antibody reacts to CD146.
Species:
Human.
Gene ID 4162

Accessory Products

Proteins and/or Positive Controls

Proteins for CD146 (10 products)

Catalog No. Species Pres. Purity   Source  

CD146

CD146 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CD146

CD146 Human Purified E. coli
  Acris Antibodies GmbH

CD146

CD146 Human Purified E. coli
  Acris Antibodies GmbH

CD146

CD146 Human Purified E. coli
  Acris Antibodies GmbH

CD146

CD146 Human
  Abnova Taiwan Corp.

CD146

CD146 Human
  Abnova Taiwan Corp.

CD146

CD146 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD146

CD146 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD146

CD146 structure and sequence Human Purified E. coli
2 µg / €310.00
  Neuromics Antibodies

CD146

CD146 structure and sequence Human Purified E. coli
5 µg / €440.00
  Neuromics Antibodies

Positive controls for CD146 (1 products)

Catalog No. Species Pres. Purity   Source  

MCAM 293T Cell Transient Overexpression Lysate(Denatured)

MCAM 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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