discontinued

NB100-63477 CD16/CD32 antibody

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100 Tests / €380.00

Quick Overview

Rat anti Mouse CD16/CD32 FCR4G8

Product Description for CD16/CD32

Rat anti Mouse CD16/CD32 FCR4G8.
Presentation: PE
Product is tested for Flow Cytometry.

Properties for CD16/CD32

Product Category Primary Antibodies
Quantity 100 Tests
Synonyms CD16a, FCG3, FCGR3A, Fc gamma receptor IIB, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, Fc-gamma-RIIB, FcR mouse Seroblock, FcRII, FcRIII, FcRIIIa, Fcgr2, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A, Low affinity immunoglobulin gamma Fc region receptor III-B, Ly-17
Presentation PE
Reactivity Ms
Applications F
Clonality Monoclonal
Clone FCR4G8
Host Rat
Isotype IgG2b
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
PU5 1.8 IOE7 Balb/c mouse cell line.
Isotype control SM19R
Add. information Research Areas: Stem Cell Markers, Immunology, Neuroscience
Application flow cytometry / FACS analysis, This antibody is useful for flow cytometry / FACS analysis, flow cytometry / FACS analysis
Background The lymphocyte Fc gamma receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc gamma type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying Fc gamma R+ cells, monoclonal antibodies to the Fc gamma II/III receptor have been used to block Fc receptor binding of IgG, Fc mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc gamma R for parasitic invasion.
Concentration 0.1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Label:
PE
Purification:
protein G purified
Buffer System:
0.09% Sodium Azide
Purity:
protein G purified
Specificity
Specificity:
NB100-63477 recognizes an epitope expressed by the murine low affinity Fc receptors, Fc gamma III (CD16) and Fc gamma II (CD32). In the mouse only the transmembrane form of CD16 is reported to exist, which is expressed on macrophages, NK cells, granulocytes, myeloid precursors, and subpopulations of T lymphocytes. CD32 is primarily expressed on cells of the myeloid lineage and also on mature B lymphocytes.
Species:
Mouse

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