NBP1-27949 CD16/CD32 antibody

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0.1 mg / €310.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse CD16/CD32 93

NBP1-27949

Product Description for CD16/CD32

Rat anti Mouse CD16/CD32 93.
Presentation: PE
Product is tested for Flow Cytometry, Neutralisation.

Properties for CD16/CD32

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CD16a, FCG3, FCGR3A, Fc gamma receptor IIB, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, Fc-gamma-RIIB, FcR mouse Seroblock, FcRII, FcRIII, FcRIIIa, Fcgr2, IGFR3, IgG Fc receptor III-2, Ly-17
Presentation PE
Reactivity Ms
Applications F, NEUT
Clonality Monoclonal
Clone 93
Host Rat
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Isotype control SM15R
Add. information Protect conjugated forms from light.
Application Blocking/Neutralizing, flow cytometry / FACS analysis, Flow cytometry / FACS analysis and Blocking/Neutralizing, flow cytometry / FACS analysis ≤ 0.2 ug/1^6 cells, Blocking/Neutralizing
Background The lymphocyte Fcγ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. (1, 2) The Fcγ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. (1) The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression.4 Besides identifying FcγR+ cells, monoclonal antibodies to the FcγII/III receptor have been used to block Fc receptor binding of IgG, Fc mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcγR for parasitic invasion. (4-6) The monoclonal antibody 93 recognizes a conformational epitope formed by FcγII and FcγIII receptors.
Storage Store at 4C. Do not freeze.
Format
Label:
R-Phycoerythrin
PE
Purification:
IgG purified
Buffer System:
No Preservative
Purity:
IgG purified
Specificity
Specificity:
Murine CD16/32 (CD16/Fc gamma II and CD32/FcgammaIII receptors)
Species:
Mouse

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