DM1212 CD178 / Fas Ligand antibody

See related secondary antibodies

Search for all "CD178 / Fas Ligand"

0.1 mg / €360.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human CD178 / Fas Ligand GM5F4

DM1212

More Views

  • DM1212

Product Description for CD178 / Fas Ligand

Mouse anti Human CD178 / Fas Ligand GM5F4.
Presentation: Purified
Product is tested for Flow Cytometry.

Properties for CD178 / Fas Ligand

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
Presentation Purified
Reactivity Hu
Applications F
Clonality Monoclonal
Clone GM5F4
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P48023
Immunogen:
Genetic immunisation with cDNA encoding Human FasL (extracellular domain)
GeneID:
356
Remarks:
Selection: based on recognition of the complete native protein expressed on transfected mammalian cells
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application Flow Cytometry: 1.2 µg/10e6 cells.
ELISA: 1/200-1/400.
Background The FAS ligand (FASL, CD95), a member of the tumor necrosis factor family, induces apoptosis in FAS-bearing cells (1). FASL is a type II membrane receptor with a soluble form that can be released into the extracellular fluid by proteolytic processing. Various cells express Fas, whereas FASL is expressed in activated splenocytes and thymocytes (2). In the immune system, Fas and FasL are involved in down-regulation of immune reactions as well as in T cell-mediated cytotoxicity. Malfunction of the Fas system causes lymphoproliferative disorders and accelerates autoimmune diseases, whereas its exacerbation may cause tissue destruction.
Concentration 1.0 mg/ml
General Readings
  1. Nagata S. Apoptosis mediated by the Fas system. Prog Mol Subcell Biol. 1996;16:87-103. PubMed PMID: 8822794.
  2. Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med. 1997 Dec 15;186(12):2045-50. PubMed PMID: 9396774. (Free PMC Article available, 3 images available)
  3. Nagata S and Golstein P (1995). The Fas death factor. Science 10;267(5203):1449-56
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein G
Buffer System:
Phosphate buffered saline, pH 7.2
State:
Liquid purified Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody recognizes CD178 / Fas Ligand.
Gene ID 356

Accessory Products

Proteins and/or Positive Controls

Proteins for CD178 / Fas Ligand (18 products)

Catalog No. Species Pres. Purity   Source  

CD178 / Fas Ligand

CD178 / Fas Ligand Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
CHO cells
10 µg / €239.00
  OriGene Technologies, Inc.

CD178 / Fas Ligand

CD178 / Fas Ligand Human > 90 %
Preparation: .
Purity Detail: >90%, as determined by Coomassie stained SDS-PAGE.
CHO cells
10 µg / €147.00
  OriGene Technologies, Inc.

CD178 / Fas Ligand (N-term, His-tagged)

CD178 / Fas Ligand Human > 95 % pure by SDS-PAGE gel and HPLC analyses CHO cells
  OriGene Technologies GmbH

CD178 / Fas Ligand (N-term, His-tagged)

CD178 / Fas Ligand Human > 95 % pure by SDS-PAGE gel and HPLC analyses CHO cells
  OriGene Technologies GmbH

CD178 / Fas Ligand (His-tag)

CD178 / Fas Ligand Human Purified > 95 % by SDS-PAGE & HPLC analysis CHO cells
10 µg / €330.00
  OriGene Technologies GmbH

CD178 / Fas Ligand (130-281, His-tag)

CD178 / Fas Ligand Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

CD178 / Fas Ligand (130-281, His-tag)

CD178 / Fas Ligand Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

CD178 / Fas Ligand (Extracell. Dom.)

CD178 / Fas Ligand Human > 98 % CHO cells
  OriGene Technologies GmbH

CD178 / Fas Ligand (Extracell. Dom.)

CD178 / Fas Ligand Human > 98 % CHO cells
  OriGene Technologies GmbH

CD178 / Fas Ligand

CD178 / Fas Ligand Human
  Abnova Taiwan Corp.

CD178 / Fas Ligand

CD178 / Fas Ligand Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD178 / Fas Ligand

CD178 / Fas Ligand Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD178 / Fas Ligand

CD178 / Fas Ligand Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD178 / Fas Ligand

CD178 / Fas Ligand Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD178 / Fas Ligand

CD178 / Fas Ligand Human
  Abnova Taiwan Corp.

CD178 / Fas Ligand

CD178 / Fas Ligand Human Purified > 98 % CHO cells
  Alpha Diagnostic Intl. Inc.

CD178 / Fas Ligand

CD178 / Fas Ligand Human Purified > 98 % CHO cells
  Alpha Diagnostic Intl. Inc.

CD178 / Fas Ligand (103-281)

CD178 / Fas Ligand Human HEK293 cells
  Kamiya Biomedical Company

Positive controls for CD178 / Fas Ligand (2 products)

Catalog No. Species Pres. Purity   Source  

CD178 / FAS Ligand Lysate(Denatured)

CD178 / FAS Ligand Lysate(Denatured)
  Abnova Taiwan Corp.

Fas Ligand Lysate

Western Blot: Fas Ligand Lysate [NBL1-10600] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for FASLG
  Novus Biologicals Inc.
  • LinkedIn