discontinued

NBP1-27891 CD19 (6D5) antibody

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0.25 mg / €360.00

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Rat anti Mouse CD19 (6D5) 6D5

NBP1-27891

Product Description for CD19 (6D5)

Rat anti Mouse CD19 (6D5) 6D5.
Presentation: Purified
Product is tested for Immunoprecipitation, Flow Cytometry.

Properties for CD19 (6D5)

Product Category Primary Antibodies
Quantity 0.25 mg
Synonyms Anti-B lymphocyte antigen CD19 antibody, Anti-B lymphocyte surface antigen B4 antibody, Anti-CD19 molecule antibody, Anti-Differentiation Antigen CD19 antibody, Anti-Leu 12 antibody, Anti-Leu12 antibody, anti-B4 antibody, anti-CD 19 antibody, anti-CD19 antigen antibody, anti-Lymphocyte Surface Antigen antibody, anti-MGC12802 antibody
Presentation Purified
Reactivity Ms
Applications F, IP
Clonality Monoclonal
Clone 6D5
Host Rat
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Mouse CD19-expressing K562 human erythroleukemia cells (1)
Isotype control SM15P, SM15PX
Add. information Inquire about low endotoxin, azide-free CD19 antibody
Research Areas: Immunology
Application flow cytometry / FACS analysis, immunoprecipitation, In vitro assay, Flow cytometry / FACS analysis, Immunoprecipitation and In vitro assay , flow cytometry / FACS analysis , immunoprecipitation , In vitro assay
Background CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. (1-7) Terminally differentiated plasma cells do not express CD19.1 In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. (3, 4) All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. (1, 7) Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. (7) Monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3. (1, 8)
Storage Store at 4C. Do not freeze.
Format
Purification:
IgG purified
Buffer System:
No Preservative
Purity:
IgG purified
State:
Purified
Specificity
Specificity:
CD19 B-cell differentiation antigen, Mr 95 kDa
Species:
Mouse

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