discontinued

GTX20212 CD19 [LT19] antibody

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0.2 mg / €370.00

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Mouse anti Human CD19 [LT19] LT19

GTX20212

Product Description for CD19 [LT19]

Mouse anti Human CD19 [LT19] LT19.
Presentation: Ig Fraction
Product is tested for Frozen Sections, Immunoprecipitation, Flow Cytometry.

Properties for CD19 [LT19]

Product Category Primary Antibodies
Quantity 0.2 mg
Presentation Ig Fraction
Reactivity Hu
Applications C, F, IP
Clonality Monoclonal
Clone LT19
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Application FACS, IHC-Fr, IP
Background CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10% of normal human peripheral blood cells and approximately 60% of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12% of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation. It is expressed in all B cell precursor leukemias. Recent cDNA cloning of CD19 has shown significant homology in the cytoplasmic domain of CD19 with the int1 oncogene.
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
Format
Purification:
IgG fraction
Buffer System:
PBS with 0.1% sodium azide
Purity:
IgG fraction
State:
Liquid
Ig Fraction
Specificity
Specificity:
Human - Not yet tested in other species

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