DDX0020B-50 CD205 / DEC-205 antibody

See related secondary antibodies

Search for all "CD205 / DEC-205"

50 µg / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse CD205 / DEC-205 NLDC-145

DDX0020B-50

Product Description for CD205 / DEC-205

Rat anti Mouse CD205 / DEC-205 NLDC-145.
Presentation: Biotin
Product is tested for Frozen Sections, Flow Cytometry.

Properties for CD205 / DEC-205

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6
Presentation Biotin
Reactivity Ms
Applications C, F
Clonality Monoclonal
Clone NLDC-145
Host Rat
Isotype IgG2a
Shipping to Germany, USA/Canada
PDF datasheet View Datasheet
Manufacturer Dendritics SAS

Datasheet Extract

Immunogen
Swiss Prot Num:
Q60767
Immunogen:
Mouse lymphoid tissue stroma.
GeneID:
17076
Application Flow Cytometry, IHC
Background NLDC-145 has been described as reacting specifically with a group of nonlymphoid dendritic cells including Langerhans cells (LC), veiled cells (VC), and interdigitating cells (IDC). The antibody does not react with precursor cells in bone marrow and blood. Macrophages are not stained by the antibody, but a subpopulation of Ia+ peritoneal exudate cells is recognized. It stains DC in T lymphocyte areas, including spleen white pulp but not spleen marginal zone DC or LC. The Ag is also expressed on activated macrophages and thymic cortical epithelium. DEC-205 has some similarities with mannose receptors and acts as a receptor for Ag uptake. (Kraal G., et al, J.Exp.med. 1986, 163, 981 ; Steinman RM, et al, PNAS, 2002, 99, 351-358 ; Flores-Langarica et al, PNAS, 2005, 102, 19039-19044) ATCC ref: HB-290TM.
Concentration 0.5 mg/ml
Product Citations
Originator or purchased from resellers:
  1. Kraal G, Breel M, Janse M, Bruin G. Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody. J Exp Med. 1986 Apr 1;163(4):981-97. PubMed PMID: 3950549. (Free PMC Article available)
  2. Flores-Langarica A, Meza-Perez S, Calderon-Amador J, Estrada-Garcia T, Macpherson G, Lebecque S, et al. Network of dendritic cells within the muscular layer of the mouse intestine. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19039-44. Epub 2005 Dec 16. PubMed PMID: 16361439. (Free PMC Article available, 5 images available)
  3. Rochereau N, Verrier B, Pin JJ, Genin C, Paul S. Phenotypic localization of distinct DC subsets in mouse Peyer Patch. Vaccine. 2011 May 9;29(20):3655-61. doi: 10.1016/j.vaccine.2011.03.012. Epub 2011 Mar 23. PubMed PMID: 21439318.
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Format
Label:
Biotin
Purification:
QMA Hyper D ion exchange chromatography
Buffer System:
PBS 50% glycerol
Specificity
Specificity:
Mouse dendritic cells.
Gene ID 17076
FocusOn and Reviews
FocusOns:

Accessory Products

  • LinkedIn