NBP1-22873 CD23 antibody

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Rabbit anti Human CD23


Product Description for CD23

Rabbit anti Human CD23.
Presentation: Serum
Product is tested for Paraffin Sections.

Properties for CD23

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms anti-Blast 2 antibody, anti-Blast2 antibody, anti-C type lectin domain family 4 member J antibo, anti-CD 23 antibody, anti-CD 23A antibody, anti-CD23 Antigen antibody, anti-CD23A antibody, anti-CLEC 4J antibody, anti-CLEC4J antibody, anti-FC Receptor IgE Low Affinity II Alpha Polypep, anti-FCE 2 antibody, anti-FCE2 antibody, anti-FCER 2 antibody, anti-FCER2 antibody, anti-FCER2A antibody, anti-Fc epsilon RII antibody, anti-Fc fragment of IgE low affinity II receptor f, anti-IGEBF antibody, anti-IgE Binding Factor antibody, anti-IgE Receptor Lymphocyte antibody, anti-Immunoglobulin E binding factor antibody, anti-Low Affinity Immunoglobulin Epsilon FC Recept, anti-Low affinity immunoglobulin epsilon Fc recept, anti-Ly42 antibody, anti-Lymphocyte IgE receptor antibody
Presentation Serum
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Recombinant protein encoding human CD23 40-248 aa.
Add. information Intended Use: This product is intended for qualitative immunohistochemistry with normal and neoplastic formalin-fixed, paraffin-embedded tissue sections, to be viewed by light microscopy. Clinical interpretation of staining results should be accompanied by histological studies with proper controls. Patients
Research Areas: Immunology
Application immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Paraffin and ABC, Immunohistochemistry-Paraffin, immunohistochemistry 1:25-1:50
Background The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal center cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a
Storage Store at 4C. Do not freeze.
Whole antisera
Buffer System:
Sodium Azide
Whole antisera
This reacts with a 45 kD protein. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and is strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found????

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