MAB4730 CD28 antibody

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100 reaction / €470.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Mouse CD28 CD28.2


Product Description for CD28

Mouse anti Mouse CD28 CD28.2.
Product is tested for Flow Cytometry.

Properties for CD28

Product Category Primary Antibodies
Quantity 100 reaction
Reactivity Ms
Applications F
Clonality Monoclonal
Clone CD28.2
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer Abnova Taiwan Corp.
Manufacturer certificates ISO 13485:2003

Datasheet Extract

Transfected murine cell line.
Gene Accession:
Add. information Mouse monoclonal antibody raised against CD28.
Application Flow Cyt
Storage Store at 4°C.
Aliquot to avoid repeated freezing and thawing.This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Buffer System:
In PBS (2mg/ml BSA, 0.1% sodium azide)
CD28 is a T-cell surface homodimeric 44kDa molecule that belongs to the Ig superfamily (1). CD28 is involved in cell adhesion T-B through the binding to its ligand B7/BB1, which is also the ligand for CTLA-4. CD28-B7 interaction is an important cosignal that allow T-cell proliferation and lymphokine production. CD28 is associated to a PI3 kinase activity (2). The majority of CD4+ T-cells and 50% of CD8+ T-cells express CD28 (3). The CD28.2 monoclonal antibody induces T-cell proliferation in costimulation with CD2 monoclonal antibodies (2). It also inhibits the CD4+ proliferation in the allogeneic T-cell response (2). This antibody has been studied at the Vth International Workshop on Human Leucocyte Differentiation Antigens in Boston (1993).

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