AP07790PU-N CD286 / TLR6 antibody

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50 µg / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human CD286 / TLR6

AP07790PU-N

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  • AP07790PU-N

Product Description for CD286 / TLR6

Rabbit anti Human CD286 / TLR6.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for CD286 / TLR6

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Toll-like receptor 6
Presentation Purified
Reactivity Hu
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y2C9
Immunogen:
Synthetic Peptide corresponding to 13 Amino Acids near the center of human TLR6.
GeneID:
10333
Application ELISA.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 0.5 - 1 µg/ml.
Background The Toll like receptor family in mammal comprises a family of transmembrane proteins characterised by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. These proteins recognize different microbial products during infection and serve as an important phylogenetically conserved mediator/link between the innate and adaptive immune responses. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLRs characterised so far activate the MyD88/interleukin 1 receptor associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1 10) have been described.
TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify.
Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates proinflammatory cascades, but also can lead to apoptotic responses.
Concentration 1 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Dilute only prior to immediate use.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
Phosphate Buffered Saline PBS containing 0.02% Sodium Azide as preservative.
State:
Liquid purified IgG fraction.
Purified
Specificity
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Proteins for CD286 / TLR6 (3 products)

Catalog No. Species Pres. Purity   Source  

CD286 / TLR6

CD286 / TLR6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD286 / TLR6

CD286 / TLR6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD286 / TLR6

CD286 / TLR6 Human
  Abnova Taiwan Corp.

Positive controls for CD286 / TLR6 (1 products)

Catalog No. Species Pres. Purity   Source  

TLR6 Lysate

Western Blot: TLR6 Lysate [NBL1-16955] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for TLR6.
  Novus Biologicals Inc.
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