TA336571 CD286 / TLR6 antibody

Rabbit Polyclonal TLR6 Antibody

See related secondary antibodies

Search for all "CD286 / TLR6"

0.1 ml / €393.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Primate, Rat CD286 / TLR6

Product Description for CD286 / TLR6

Rabbit anti Human, Mouse, Primate, Rat CD286 / TLR6.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for CD286 / TLR6

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms Toll-like receptor 6
Presentation Purified
Reactivity Hu, Ms, Prim, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y2C9
Immunogen:
Synthetic peptide made to a C-terminal portion of the human TLR6 protein (within residues 700-796). [Swiss-Prot# Q9Y2C9].
GeneID:
10333
Application WB: 1:1000-1:2000
Background TLR6 (toll-like receptor 6, also called CD286) belongs the family of TLRs which are membrane receptors with potential of acting as gatekeepers of the inte immunity through recognizing microbial components and initiating activation of an adequate immune response. Localized in cell membrane as well as in cytoplasmic vesicle/phagosome membrane as single-pass type I membrane protein, TLR6 is expressed in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. TLR6 participates in the inte immune response to Gram-+ve bacteria and fungi. It specifically recognize diacylated/triacylated lipopeptides, and has the ability to recognize mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor, phenol-soluble modulin and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It acts via MYD88 and TRAF6, leading to NFkB activation, cytokine secretion and inflammatory response. Moreover, it has been shown to bind MYD88 and dimerize with TLR2, wherein TLR6- TLR2 heterodimers recognize a large number of lipidcontaining molecules and transducers inflammatory siglling in a variety of cell type.
Format
Purification:
Immunogen affinity purified
Buffer System:
Tris-citrate/phosphate, pH 7, 0.09% Sodium azide. Store at 4C. Do not freeze.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for CD286 / TLR6 (3 products)

Catalog No. Species Pres. Purity   Source  

CD286 / TLR6

CD286 / TLR6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD286 / TLR6

CD286 / TLR6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD286 / TLR6

CD286 / TLR6 Human
  Abnova Taiwan Corp.

Positive controls for CD286 / TLR6 (1 products)

Catalog No. Species Pres. Purity   Source  

TLR6 Lysate

Western Blot: TLR6 Lysate [NBL1-16955] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for TLR6.
  Novus Biologicals Inc.
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