NBP1-22528 CD31 / PECAM1 antibody

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Mouse anti Human CD31 / PECAM1 JC/70A


Product Description for CD31 / PECAM1

Mouse anti Human CD31 / PECAM1 JC/70A.
Presentation: Supernatant
Product is tested for Paraffin Sections.

Properties for CD31 / PECAM1

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms EndoCAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
Presentation Supernatant
Reactivity Hu
Applications P
Clonality Monoclonal
Clone JC/70A
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

B/C mice were immunized with membrane preparation of a spleen from a patient with hairy cell leukemia.
Application immunohistochemistry, ABC, immunohistochemistry 1:10-1:25
Background CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
Storage Store at 4C. Do not freeze.
Tissue culture supernatant
Buffer System:
Sodium Azide
Tissue culture supernatant
This reacts with a 100 kD glycoprotein expressed by endothelial cells and 130 kD glycoprotein present in platelets. It stains endothelial cells in normal as well as malignant tissues.

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