SM2180A CD4 (Domain 1) antibody

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1 mg / €810.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Rat CD4 OX-38

Product Description for CD4

Mouse anti Rat CD4 OX-38.
Properties: (Domain 1)
Presentation: Azide Free
Product is tested for Frozen Sections, Flow Cytometry.

Properties for CD4

Product Category Primary Antibodies
Target Category
Quantity 1 mg
Synonyms T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Presentation Azide Free
Reactivity Rt
Applications C, F
Clonality Monoclonal
Clone OX-38
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P05540
Immunogen:
MLR generated rat T cells. Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line
GeneID:
24932
Property Domain 1
Application Flow Cytometry: 1/100 - 1/200;
Immunohistochemistry on frozen sections.
Immunoprecipitation.
Background CD4 is a 55kD glycoprotein expressed by T helper cells, monocytes and macrophages.
Concentration 1.0 mg/ml
General Readings
  1. Jefferies, W.A. et al. (1985) Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages. J. Exp. Med. 162:117-127.
  2. Barclay AN. The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology. 1981 Apr;42(4):593-600. PubMed PMID: 7016746. (Free PMC Article available)
  3. Thomas ML, Green JR. Molecular nature of the W3/25 and MRC OX-8 marker antigens for rat T lymphocytes: comparisons with mouse and human antigens. Eur J Immunol. 1983 Oct;13(10):855-8. PubMed PMID: 6416869.
  4. Hall, B.M. et al. (1998) Anti-CD4 Monoclonal Antibody- Induced Tolerance to MHC-Incompatible Cardiac Allografts Maintained by CD4+ Suppressor T cells that are not Dependent upon IL-4.
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography on Protein G
Buffer System:
PBS, pH7.4
State:
Liquid purified IgG
Azide Free
Specificity
Specificity:
This antibody recognises the CD4 cell surface antigen. Clone MRC OX-38 competes for binding with clone W3/25.
Species:
Rat.

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