SM435F CD4 antibody

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0.1 mg / €530.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Bovine CD4 CC8

Product Description for CD4

Mouse anti Bovine CD4 CC8.
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for CD4

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Presentation FITC
Reactivity Bov
Applications F
Clonality Monoclonal
Clone CC8
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
A7YY52
Immunogen:
Spleen cells from an immunised mouse were fused with cells of the mouse NS1 myeloma cell line.
GeneID:
407098
Application Flow Cytometry.
Background CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Concentration 0.1 mg/ml
General Readings
  1. Bensaid, A. et al. (1991) Individual antigens of cattle. Bovine CD4 (BoCD4). Vet. Immunol. Immunopathol. 27:51 - 54.
  2. Eskra L, O'Reilly KL, Splitter GA. Effect of monoclonal antibodies on in vitro function of T-cell subsets. Vet Immunol Immunopathol. 1991 Jan;27(1-3):215-22. PubMed PMID: 1826982.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Format
Label:
Fluorescein Isothiocyanate Isomer 1
FITC
Purification:
Affinity chromatography on Protein G
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
State:
Liquid purified IgG
Specificity
Specificity:
CC8 precipitates a molecule of approximately 50kD and is considered to be the bovine homologue of Human CD4. The phenotype, tissue distribution and function of T-cells expressing the bovine CD4 antigen are similar to those in other species. However, expression on macrophages has not yet been detected.
Species:
Bovine.
Gene ID 407098

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