SM587 CD4 antibody

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0.25 ml / €470.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Guinea Pig CD4 CT7

SM587

Product Description for CD4

Mouse anti Guinea Pig CD4 CT7.
Presentation: Supernatant
Product is tested for Frozen Sections, Flow Cytometry.

Properties for CD4

Product Category Primary Antibodies
Quantity 0.25 ml
Synonyms T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, T4/Leu-3
Presentation Supernatant
Reactivity GP
Applications C, F
Clonality Monoclonal
Clone CT7
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Guinea pig peritoneal T-cells. Spleen cells from immunised BALB/c mice were fused with cells of the X63.Ag8.653 mouse myeloma cell line.
Application Immunohistochemistry on Frozen Sections: 1/10-1/100.
Flow Cytometry: 1/10-1/100.
Background CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Concentration 1.0 mg/ml
General Readings
  1. Tan BT, Ekelaar F, Luirink J, Rimmelzwaan G, De Jonge AJ, Scheper RJ. Production of monoclonal antibodies defining guinea pig T-cell surface markers and a strain 13 Ia-like antigen: the value of immunohistological screening. Hybridoma. 1985 Summer;4(2):115-24. PubMed PMID: 3891587.
  2. Baker D, Karcher K, Antoniou AV, Turk JL, Tan BT, Scheper RJ. Changes in lymphocyte subsets after treatment with cyclophosphamide and during the development of contact sensitivity in the guinea pig. Int J Immunopharmacol. 1987;9(2):175-83. PubMed PMID: 2884193.
  3. Liversidge J, Forrester JV. Experimental autoimmune uveitis (EAU): immunophenotypic analysis of inflammatory cells in chorio retinal lesions. Curr Eye Res. 1988 Dec;7(12):1231-41. PubMed PMID: 3229134.
  4. 4 . Steerenburg, P.A. et al. (1991). Tumour rejection after transfer of line 10 immunity is mediated by two T-cell populations. Cancer Immun. Immunother. 34: 103-110.
  5. Debout C, Griveau AM, Izard J. The Kurloff cell in estrogenized guinea pigs as a CT7+ 8BE6- CT6- MR-1- CT10- IgM- lymphocyte with natural killer activity. Nat Immun Cell Growth Regul. 1991;10(6):327-35. PubMed PMID: 1787838.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Concentrated Tissue Culture Supernatant Containing 0.09% Sodium Azide and 1.0% BSA.
Supernatant
Specificity
Specificity:
This antibody recognises the CD4 antigen present on T Helper/Inducer lymphocytes.
Species:
Guinea Pig.

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