NB100-62112 CD43 / Leukosialin antibody

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Mouse anti Sheep CD43 / Leukosialin CO.44B8


Product Description for CD43 / Leukosialin

Mouse anti Sheep CD43 / Leukosialin CO.44B8.
Presentation: Supernatant
Product is tested for Agglutination, Functional assay.

Properties for CD43 / Leukosialin

Product Category Primary Antibodies
Quantity 2 ml
Synonyms CD43, GALGP, Galactoglycoprotein, Leukocyte sialoglycoprotein, Leukosialin, SPN, Sialophorin
Presentation Supernatant
Reactivity Sh
Applications AGG, FN
Clonality Monoclonal
Clone CO.44B8
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Made to Sheep CD43
Application Aggregation, Functional, This antibody is useful for Functional, Aggregation, Functional Aggregation
Background CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tissue culture supernatant
Buffer System:
Sodium Azide
Tissue culture supernatant
CD43 (CO.44B8)

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