VISC39-01 CD45 antibody

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Mouse anti Rabbit CD45 ISC39A


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  • VISC39-01

Product Description for CD45

Mouse anti Rabbit CD45 ISC39A.
Presentation: Ascites
Product is tested for Flow Cytometry.

Properties for CD45

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CD45R, CD45RA, CD45RB, CD45RO, L-CA, Leukocyte common antigen, PTPRC, T200
Presentation Ascites
Reactivity Rb
Applications F
Clonality Monoclonal
Clone ISC39A
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer VMRD Inc.

Datasheet Extract

Application Suitable for Flow cytometry and cell function.
Background CD45 proteins are expressed at high levels on all cells of hematopoietic origin, except erythrocytes. CD45 is a major component of the glycocalyx. Expression is high on lymphocytes with 10% of their surface area comprising CD45. Expression is abundant but is lower on other leukocytes. Expression of different isoforms differs on differentiated subsets of hematopoietic cells like CD45RA on naive/resting T cells and on medullary thymocytes, and on CD45R0 on memory/activated T cells and on cortical thymocytes. The isoform pattern can change in response to cytokines. Multiple isoforms may occur on a single cell type. ISC39A recognizes an epitope expressed on all isoforms. The pattern of labeling observed in 2 parameter dot plots in flow cytometry is identical to the pattern of labeling observed with anti-CD45 mAbs in humans and cattle. ISC18A blocks labeling with ISC39A.
Concentration 1.0 mg/ml
Storage When the vial is stored at 2-8°C, it should be stable for one year.
Ascites fluid, clarified by centrifugation, and filtered through a 0.2 μM filter
Buffer System:
In phosphate buffered saline, preserved with sodium azide.
This antibody detects CD45. It labels 100 % PBMC.

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