NB100-64998 CD45RA antibody

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Mouse anti Rat CD45RA OX-33


Product Description for CD45RA

Mouse anti Rat CD45RA OX-33.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Flow Cytometry, Paraffin Sections.

Properties for CD45RA

Product Category Primary Antibodies
Quantity 1 mg
Synonyms CD45, EC, L-CA, LCA, Leukocyte Common Antigen, PTPRC, T200
Presentation Aff - Purified
Reactivity Rt
Applications C, F, P
Clonality Monoclonal
Clone OX-33
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application Immunohistochemistry-Frozen, flow cytometry / FACS analysis, Immunohistochemistry-Paraffin
Background CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Affinity Purified
Affinity Purified
Aff - Purified
Rat. Not yet tested in other species.

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