SM036RT CD48 antibody

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25 Tests / €210.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse CD48 OX-78

SM036RT

Product Description for CD48

Rat anti Mouse CD48 OX-78.
Presentation: PE
Product is tested for Flow Cytometry.

Properties for CD48

Product Category Primary Antibodies
Target Category
Quantity 25 Tests
Synonyms B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1
Presentation PE
Reactivity Ms
Applications F
Clonality Monoclonal
Clone OX-78
Host Rat
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P18181
Immunogen:
Recombinant soluble mouse CD48. Spleen cells from immunised AO Rats immunised were fused with cells from the Rat Y3 myeloma cell line.
GeneID:
12506
Application Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Background CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.
General Readings
  1. Kato K, Koyanagi M, Okada H, Takanashi T, Wong YW, Williams AF, et al. CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J Exp Med. 1992 Nov 1;176(5):1241-9. PubMed PMID: 1383383. (Free PMC Article available)
Storage Prior to and following reconstitution store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Format
Label:
R. Phycoerythrin (RPE)
PE
Purification:
Affinity chromatography on Protein G
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
State:
Lyophilized purified IgG fraction.
Reconstitution:
Restore with 0.25 ml distilled water
Specificity
Specificity:
This antibody labels thymocytes, B and T cells and macrophages.
CD48 is a ligand for the mouse CD2 cell surface antigen.
Species:
Mouse.
Gene ID 12506

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