TA319627 CD48 (Center) antibody

Rabbit Polyclonal SLAMF2 Antibody

See related secondary antibodies

Search for all "CD48"

0.1 mg / €371.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat CD48

Product Description for CD48

Rabbit anti Human, Mouse, Rat CD48.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for CD48

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P09326
Immunogen:
19 amino acid peptide near the center of human CD48 / SLAMF2
GeneID:
962
Property Center
Application ELISA.
Western blot: 1-2 µg/ml.
Positive control: Rat Lung Tissue Lysate.
Background The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
General Readings
  1. Smith GM, Biggs J, Norris B, Anderson-Stewart P, Ward R. Detection of a soluble form of the leukocyte surface antigen CD48 in plasma and its elevation in patients with lymphoid leukemias and arthritis. J Clin Immunol. 1997 Nov;17(6):502-9. PubMed PMID: 9418191.
  2. Sidorenko SP and Clark EA. The dual-function CD150 receptor sub-family: the viral attraction. Nat. Immunol. 4:19-24.
  3. Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, et al. CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J Immunol. 2006 Jul 1;177(1):77-83. PubMed PMID: 16785501.
  4. Fukushima K, Ikehara Y, Yamashita K. Functional role played by the glycosylphosphatidylinositol anchor glycan of CD48 in interleukin-18-induced interferon-gamma production. J Biol Chem. 2005 May 6;280(18):18056-62. Epub 2005 Mar 10. PubMed PMID: 15760905.
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat
Specificity
Specificity:
This antibody detects CD48 / SLAMF2 at center.
Two isoforms of SLAMF2 are known to exist; this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.

Accessory Products

Proteins and/or Positive Controls

Proteins for CD48 (6 products)

Catalog No. Species Pres. Purity   Source  

CD48

CD48 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

CD48

CD48 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD48

CD48 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD48

CD48 Human Purified
  Abnova Taiwan Corp.

CD48

CD48 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD48

CD48 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for CD48 (3 products)

Catalog No. Species Pres. Purity   Source  

CD48 293T Cell Transient Overexpression Lysate(Denatured)

CD48 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

CD48 Lysate

Western Blot: CD48 Lysate [NBL1-08955] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CD48
  Novus Biologicals Inc.

CD48 overexpression lysate

CD48 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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