NB100-64910 CD5 antibody

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1 ml / €430.00

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Mouse anti Equine CD5 CVS5

Product Description for CD5

Mouse anti Equine CD5 CVS5.
Presentation: Supernatant
Product is tested for Frozen Sections, Flow Cytometry, Paraffin Sections.

Properties for CD5

Product Category Primary Antibodies
Quantity 1 ml
Synonyms LEU-1, LEU1, Ly-1, Lymphocyte antigen T1/Leu-1, Lyt-1, T-cell surface glycoprotein CD5
Presentation Supernatant
Reactivity Eq
Applications C, F, P
Clonality Monoclonal
Clone CVS5
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Equine leucocytes
Application flow cytometry / FACS analysis, Immunohistochemistry-Frozen, Immunohistochemistry-Frozen and Flow cytometry / FACS analysis, Immunohistochemistry-Frozen flow cytometry / FACS analysis
Background In humans, CD5 is a 67kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tissue culture supernatant
Buffer System:
0.09% Sodium Azide
Tissue culture supernatant
Reacts with equine T lymphocytes but does not recognize B lymphocytes.

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