AP05583PU-S CD5L (C-term) antibody

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50 µg / €350.00

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Rabbit anti Human, Mouse CD5L


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  • AP05583PU-S

Product Description for CD5L

Rabbit anti Human, Mouse CD5L.
Properties: (C-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for CD5L

Product Category Primary Antibodies
Quantity 50 µg
Synonyms SP-ALPHA
Presentation Purified
Reactivity Hu, Ms
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

13 amino acid peptide sequence near the carboxy terminus of human CD5L.
Property C-term
Application Western blot: 0.5 - 1.0 µg/ml; detects a band of approximately 38kDa in Raji cell lysates.
Immunohistochemistry on paraffin sections.
Background CD5L is also known as Apoptosis Inhibitor expressed by Macrophages (AIM), and SP alpha. CD5L is a soluble 38kD glycoprotein which is specifically produced by mature macrophages, and has been shown to support their survival and enhance phagocytic function. CD5L expression is upregulated in response to LXR/RXR heterodimer activation.
CD5L has been shown to mediate the survival of macrophages in atherosclerotic plaques.
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Concentration 1.0mg/ml
General Readings
  1. Sarrias MR, Roselló S, Sánchez-Barbero F, Sierra JM, Vila J, Yélamos J, et al. A role for human Sp alpha as a pattern recognition receptor. J Biol Chem. 2005 Oct 21;280(42):35391-8. Epub 2005 Jul 19. PubMed PMID: 16030018.
  2. Arai S, Shelton JM, Chen M, Bradley MN, Castrillo A, Bookout AL, et al. A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development. Cell Metab. 2005 Mar;1(3):201-13. PubMed PMID: 16054063.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
Phosphate buffered saline containing 0.02% Sodium Azide
Liquid purified IgG
This antibody detects an epitope within the C-terminal (CT) region of human CD5L.
Human, Mouse.

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