discontinued

SM2134P CD8 antibody

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0.25 mg / €450.00

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Mouse anti Rabbit CD8 12.C7

SM2134P

Product Description for CD8

Mouse anti Rabbit CD8 12.C7.
Presentation: Purified
Product is tested for Flow Cytometry.

Properties for CD8

Product Category Primary Antibodies
Quantity 0.25 mg
Synonyms T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-lymphocyte differentiation antigen T8/Leu-2
Presentation Purified
Reactivity Rb
Applications F
Clonality Monoclonal
Clone 12.C7
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control AM03095PU-N
Application Flow Cytometry: 1/100 - 1/200; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Concentration 1.0 mg/ml
General Readings 1. Civin, C.I. et al (1984) Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. 133(1):
157-165
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography on protein G
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide
State:
Liquid purified IgG
Purified
Specificity
Specificity:
This antibody recognises the rabbit CD8 cell surface antigen, expressed by a subset of T lymphocytes with cytotoxic/suppressor activity.
Species:
Rabbit.

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