AP26041PU-S Cdc25B pSer149 antibody

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50 µl / €240.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Mouse, Rat Cdc25B

Product Description for Cdc25B

Rabbit anti Mouse, Rat Cdc25B.
Properties: pSer149
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Cdc25B

Product Category Primary Antibodies
Quantity 50 µl
Presentation Aff - Purified
Reactivity Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Peptide sequence around phosphorylation site of Serine 149 derived from Mouse Cdc25B.
AA Sequence:
Property pSer149
Add. information Molecular weight: 62
Application Western blot: 1:500 - 1:1000.
Background Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Concentration 1.0 mg/ml
General Readings
  1. Li G, et al. (2010) Retrovirology.7:59.
  2. Wang Z,et al. (2010) BMC Cancer.10:233.
  3. Lucci MA,et al. (2010) Cell Oncol.32(5-6):361-72.
Storage Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity-chromatography using epitope-specific peptide
Buffer System:
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Mouse, rat
This antibody detects endogenous level of Cdc25B protein only when phosphorylated at serine 149.
Gene ID 12531

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