discontinued

AP00031PU-N CDC42 / Rac-1 antibody

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0.1 mg / €390.00

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Rabbit anti Bovine, Human, Mouse, Rat CDC42 / Rac-1

AP00031PU-N

Product Description for CDC42 / Rac-1

Rabbit anti Bovine, Human, Mouse, Rat CDC42 / Rac-1.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for CDC42 / Rac-1

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Bov, Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptides surrounding amino acid 144 of human cdc42
Application Western Blot: 0.5-4 μg/ml.
Immunohistochemistry: 10-20 μg/ml.
Background cdc42/Rac belongs to the superfamily of small GTPases that are structurally linked to the proto-oncogene product p21ras and are important for the control of cell growth and differentiation as well as for intracellular organization. Cdc42/Rac is an important upstream regulator of the protein kinase cascade that controls the SAPK/JNK and p38 activity. Recent data also suggest that constitutive active forms of cdc42 can induce apoptosis through a mechanism requiring signaling through SAPK/JNK.
Concentration 0.2 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -20°C to -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity purified
Buffer System:
PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
State:
Liquid purified Ig
Aff - Purified
Specificity
Specificity:
The antibody detects recombinant human Rac and cdc42 proteins (Rho subfamily), and does not cross-react with members of the Ras or Rab family proteins. The antibody specificity is confirmed by specific peptide inhibition in immunoblotting studies.
Species:
Human, Mouse, Rat, Bovine.

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