NBP1-22798 CDw75 antibody

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Mouse anti Human CDw75 LN-1

Product Description for CDw75

Mouse anti Human CDw75 LN-1.
Product is tested for Paraffin Sections.

Properties for CDw75

Product Category Primary Antibodies
Quantity 6 ml
Synonyms B-Cell marker, alpha 2.6 - sialylated carbohydrate
Reactivity Hu
Applications P
Clonality Monoclonal
Clone LN-1
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Research Areas: Cellular Markers
Application immunohistochemistry, Immunohistochemistry-Paraffin, This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded and acetone fixed cryostat tissue sections. No further titration is required., immunohistochemistry , Immunohistochemistry-Paraffin
Background The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi apparatus but which can be proteolytically processed to a soluble form, is involved in the generation of the cell surface carbohydrate determinants and differentiation antigens HB6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene. This antibody recognizes the CD75 cell surface antigen, an alpha 2,6 sialyated carbohydrate epitope expressed by mature B cells, especially germinal centre B cells, red blood cells and some epithelial cells.
Storage Store at 4C. Do not freeze.
IgM purified
Buffer System:
No Preservative
IgM purified
This reacts with a 45-85 kD antigen present on B cells derived from the germinal center. It reacts with epithelial cells of breast, prostate, kidney, pancreas, and lung. This is an excellent marker for the identification of germinal center derived B cell ????

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