AP03010PU-N cfp10 / esxB antibody

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0.1 mg / €260.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti cfp10 / esxB

Product Description for cfp10 / esxB

Rabbit anti cfp10 / esxB.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for cfp10 / esxB

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms 10 kDa culture filtrate antigen cfp10, ESAT-6-like protein esxB, MT3988, MTV027.09, Rv3874, Secreted antigenic protein MTSA-10, lhp, mtsA10
Presentation Aff - Purified
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P0A566
Immunogen:
CFP10 (Rv3874) of Mycobacterium tuberculosis
GeneID:
886194
Application Suitable for Western Blotting under Reducing conditions: 0.2-1 μg/ml.
Background CFP10 (10 kDa culture filtrate protein) is a low molecular weight protein isolated from Mycobacterium tuberculosis culture filtrates. CFP10 and the 6 kDa early secretory antigen of T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG).
CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, that appear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity.
Concentration 1.0 mg/ml
General Readings
  • Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998 Jun 11;393(6685):537-44. PubMed PMID: 9634230.
  • Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A: Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ). J Immunol. 2012 May 15;188(10):5020-31.
  • Yang H, Chen H, Liu Z, Ma H, Qin L, Jin R, Zheng R, Feng Y, Cui Z, Wang J, Liu J, Hu Z: A novel B-cell epitope identified within Mycobacterium tuberculosis CFP10/ESAT-6 protein. PLoS One. 2013;8(1):e52848.
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.
Format
Purification:
Protein-A affinity chromatography.
Buffer System:
PBS, pH 7.4 with 15 mM sodium azide as preservative.
State:
Liquid purified IgG fraction (> 95% pure by SDS-PAGE).
Aff - Purified
Specificity
Specificity:
The polyclonal antibody reacts with CFP10 (LHP), a 12,3 kDa antigen encoded by gene Rv3874 of Mycobacterium tuberculosis.
The antibody recognizes CFP10 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis; it reacts also with recombinant antigen produced in Escherichia coli.
Gene ID 886194

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