AM50404PU-N CHD5 antibody

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Rat anti Human CHD5 5A10

Product Description for CHD5

Rat anti Human CHD5 5A10.
Presentation: Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for CHD5

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Chd5 protein, Chromodomain helicase DNA-binding protein 5
Presentation Purified
Reactivity Hu
Applications C, ICC/IF, WB
Clonality Monoclonal
Clone 5A10
Host Rat
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
KLH-conjugated linear peptide corresponding to mouse CHD5.
Isotype control SM15P, SM15PX
Application Immunohistochemistry: A representative lot from an independent laboratory detected CHD5 in E12.5 mouse gut tissue. (Yoshimura, S., et al. (2010). Hybridoma. 29(1):636-66).
Western Blot: A representative lot detected CHD5 in L929, HeLa, Cos1, Y1, MCF7, and C2C12 cells, and in E12.5 mouse tissue lysate.
Immunocytochemistry: A representative lot from an independent laboratory detected CHD5 in HeLa and L929 cells (Yoshimura, S., et al. (2010). Hybridoma. 29(1):636-66).
Background Chromodomain helicase DNA-binding protein 5 (CHD5) is a novel ATP-dependent chromatin remodeling factor. In normal cells CHD5 plays a role in apoptosis, cell proliferation, and aging, through modulation of the p19(Arf)/p53 pathway. However, CHD5 is downregulated in various cancer cell lines, possibly due to hypermethylation of the CHD5 promoter and miRNA-211 activity, indicating that it may also play a critical role as a tumor suppressor.
Concentration lot-specific
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatc
Protein G Chromatography
Buffer System:
0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Liquid purified Ig fraction
Demonstrated to react with Human. Predicted to react with Mouse based upon immunogen design.

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