NB100-2037 Chromogranin A + B antibody

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0.25 ml / €590.00

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Rabbit anti Human, Mouse, Rabbit, Rat Chromogranin A + B


Product Description for Chromogranin A + B

Rabbit anti Human, Mouse, Rabbit, Rat Chromogranin A + B.
Presentation: Serum
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections.

Properties for Chromogranin A + B

Product Category Primary Antibodies
Quantity 0.25 ml
Presentation Serum
Reactivity Hu, Ms, Rb, Rt
Applications C, ICC/IF, P
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Isolated from human Pheochromocytoma.
Application Immunohistochemistry-Paraffin , Immunohistochemistry-Frozen
Background Chromogranins are acidic glycoproteins co-stored and co-released with peptides and amines in a variety of neuroendocrine tissues, both normal and neoplastic. This polyclonal antibody recognizes chromogranin A and B. This dual specificity makes it a potent marker of peptide hormone-producing endocrine cells and tumors. Specific reactivity with pituitary antrum, duodenum, small intestines and pancreas when used in immunohistochemistry.
General Readings Desnos C et al. Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol 163:559-70 (2003). PubMed PMID: 14610058
General / background references:Larsson et al. Endocrin Pathol 1:14 (1992).Eriksson B et al. A polyclonal antiserum against chromogranin A and B--a new sensitive marker for neuroendocrine tumours. Acta Endocrinol (Copenh) 122:145-55 (1990). PubMed PMID: 2316306
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Whole antisera
Buffer System:
PBS with 1%BSA
Whole antisera
Cross-reacts with Human, Rabbit, Rat and Mouse. Not yet tested in other species.

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