discontinued

GTX28402 CIDE A antibody

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0.1 mg / €400.00

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Rabbit anti Mouse CIDE A

GTX28402

Product Description for CIDE A

Rabbit anti Mouse CIDE A.
Presentation: Ig Fraction
Product is tested for Western blot / Immunoblot.

Properties for CIDE A

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CIDE-A, CIDEA, Cell Death-inducing DFFA-like Effector A
Presentation Ig Fraction
Reactivity Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide, corresponding to amino acids 200-214 of Mouse CIDE A.
Application WB
Background Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase-activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (GT28403) were recently identified (1). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains ofDFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.
Concentration 0.5 mg/ml
Storage Keep as concentrated solution, aliquot and store at 4
Format
Purification:
IgG fraction
Buffer System:
PBS with 0.02% sodium azide
Purity:
IgG fraction
State:
Ig Fraction
Specificity
Specificity:
Cross-reacts with Mouse. Not yet tested in other species.

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