NB100-55817 CIDE A (C-term) antibody

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0.1 mg / €400.00

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Rabbit anti Mouse CIDE A


Product Description for CIDE A

Rabbit anti Mouse CIDE A.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for CIDE A

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CIDE-A, CIDEA, Cell Death-inducing DFFA-like Effector A
Presentation Aff - Purified
Reactivity Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Murine mCIDE-A (CT) peptide.
Property C-term
Background Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.?DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.
Storage Store at 4C. Do not freeze.
Peptide Affinity Purified
Buffer System:
PBS containing 0.02% sodium azide.
Peptide Affinity Purified
Aff - Purified
Mouse Not yet tested in other species.

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