discontinued

NBP1-03231 CIDEB antibody

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50 µg / €480.00

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Rabbit anti Human, Mouse, Rat CIDEB

NBP1-03231

Product Description for CIDEB

Rabbit anti Human, Mouse, Rat CIDEB.
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for CIDEB

Product Category Primary Antibodies
Quantity 50 µg
Synonyms anti-CIDEB antibody
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B
Application Immunohistochemistry-Paraffin, Western Blot, This antibody is useful for the following applications and at the following dilutions: Western Blot, Immunohistochemistry-Paraffin 5 ug/ml, Western Blot, Immunohistochemistry-Paraffin 5 ug/ml,
Background Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.
Concentration 1 mg/ml
Format
Buffer System:
0.02% Sodium Azide
Specificity
Specificity:
Peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B
Species:
Human, Mouse, Rat

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