AM26360PU-N Clara cell protein (CC16) antibody

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0.1 mg / €390.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Clara cell protein (CC16) AY1E6

AM26360PU-N

Product Description for Clara cell protein (CC16)

Mouse anti Human Clara cell protein (CC16) AY1E6.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections, Frozen Sections, Enzyme Immunoassay.

Properties for Clara cell protein (CC16)

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Urinary protein 1
Presentation Purified
Reactivity Hu
Applications C, E, P, WB
Clonality Monoclonal
Clone AY1E6
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control AM03095PU-N, SM10P (for use in human samples)
Application Immunohistochemistry on frozen sections: The typical starting working dilution is 1:50.
Immunohistochemistry on paraffin sections: The typical starting working dilution is 1:50.
Immunoassays.
Western blot: The typical starting working dilution is 1:50.
Background Clara cell protein or urinary protein 1 is a homodimeric protein of 16 kD and is secreted predominantly by Clara cells in terminal bronchioles and from puberty on in the male urogenital tract. CC16 is formed by two chains, each with a molecular weight of 7.9 kD. CC16 occurs in very high concentrations in respiratory tract derived fluids such as sputum or bronchoalveolar lavage fluid. CC16 occurs also in urogenital secretions, such as amniotic fluid, urine and semen. The protein difusses passively into serum. CC16 behaves like an anti-cytokine by downregulating the production of IFN-gamma, IL-1 and TNF-alpha by stimulated leukocytes. Besides this, CC16 reduces the antiviral activity and the augmentation of phagocytosis induced by IFN-gamma.
Concentration 0.1 mg/ml
General Readings
  1. Geerts L, Jorens PG, Willems J, De Ley M, Slegers H. Natural inhibitors of neutrophil function in acute respiratory distress syndrome. Crit Care Med. 2001 Oct;29(10):1920-4. PubMed PMID: 11588452.
Storage

Store at 2 - 8 °C.
Shelf life: one year from despatch.

Format
Purification:
Protein G
Buffer System:
PBS
Preservatives:
0.02% sodium azide
Stabilizers:
0.1% bovine serum albumin
State:
Liquid 0.2 µm filtered Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:

The monoclonal antibody AY1E6 recognizes the anti-inflammatory mediator Clara cell protein (CC16).

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