AP06060PU-N Claudin-1 / CLDN1 antibody

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0.1 mg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Claudin-1 / CLDN1

AP06060PU-N

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  • AP06060PU-N

Product Description for Claudin-1 / CLDN1

Rabbit anti Human, Mouse, Rat Claudin-1 / CLDN1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Properties for Claudin-1 / CLDN1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CLD1, PRO944, SEMP1, Senescence-associated epithelial membrane protein, UNQ481
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~22 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O95832
Immunogen:
Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-1.
GeneID:
9076
Application Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Immunofluorescence: 1/50-1/200.
Background The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tigh junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
Phosphate buffered saline (PBS), pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of Claudin-1 protein.
(region surrounding Arg197)
Gene ID 9076
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Accessory Products

Proteins and/or Positive Controls

Proteins for Claudin-1 / CLDN1 (3 products)

Catalog No. Species Pres. Purity   Source  

Claudin-1 / CLDN1

Claudin-1 / CLDN1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Claudin-1 / CLDN1

Claudin-1 / CLDN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Claudin-1 / CLDN1

Claudin-1 / CLDN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Claudin-1 / CLDN1 (3 products)

Catalog No. Species Pres. Purity   Source  

Claudin 1 Lysate

Western Blot: Claudin 1 Lysate [NBL1-09235] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CLDN1
  Novus Biologicals Inc.

CLDN1 293T Cell Transient Overexpression Lysate(Denatured)

CLDN1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

CLDN1 HEK293 Cell Transient Overexpression Lysate (Non-Denatured)

CLDN1 HEK293 Cell Transient Overexpression Lysate (Non-Denatured) Transient overexpression cell lysate was tested with Anti-CLDN1 antibody (H00009076-M01) by Western Blots.
  Abnova Taiwan Corp.
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