AP13330PU-N Claudin-1 / CLDN1 (Loop1) antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human Claudin-1 / CLDN1

AP13330PU-N

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  • AP13330PU-N

Product Description for Claudin-1 / CLDN1

Rabbit anti Human Claudin-1 / CLDN1.
Properties: (Loop1)
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Claudin-1 / CLDN1

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms CLD1, PRO944, SEMP1, Senescence-associated epithelial membrane protein, UNQ481
Presentation Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O95832
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Loop1 region of human CLDN1.
GeneID:
9076
Property Loop1
Application ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Immunohistochemistry: 1/10 - 1/50.
Background Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration lot specific
General Readings
  1. Kinugasa,T., Anticancer Res. 27 (6A), 3729-3734 (2007)
  2. Paschoud,S., Mod. Pathol. 20 (9), 947-954 (2007)
  3. Morohashi,S., Int. J. Mol. Med. 20 (2), 139-143 (2007)
  4. Krajewska,M., Prostate 67 (9), 907-910 (2007)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to Claudin 1 (CLDN1).
Species:
Human.
Gene ID 9076
FocusOn and Reviews
Reviews:

Accessory Products

Proteins and/or Positive Controls

Proteins for Claudin-1 / CLDN1 (3 products)

Catalog No. Species Pres. Purity   Source  

Claudin-1 / CLDN1

Claudin-1 / CLDN1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Claudin-1 / CLDN1

Claudin-1 / CLDN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Claudin-1 / CLDN1

Claudin-1 / CLDN1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Claudin-1 / CLDN1 (3 products)

Catalog No. Species Pres. Purity   Source  

Claudin 1 Lysate

Western Blot: Claudin 1 Lysate [NBL1-09235] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CLDN1
  Novus Biologicals Inc.

CLDN1 293T Cell Transient Overexpression Lysate(Denatured)

CLDN1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

CLDN1 HEK293 Cell Transient Overexpression Lysate (Non-Denatured)

CLDN1 HEK293 Cell Transient Overexpression Lysate (Non-Denatured) Transient overexpression cell lysate was tested with Anti-CLDN1 antibody (H00009076-M01) by Western Blots.
  Abnova Taiwan Corp.
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