AP06065PU-N Claudin-4 / CLDN4 antibody

See related secondary antibodies

Search for all "Claudin-4 / CLDN4"

0.1 mg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat Claudin-4 / CLDN4

AP06065PU-N

More Views

  • AP06065PU-N

Product Description for Claudin-4 / CLDN4

Rabbit anti Human, Mouse, Rat Claudin-4 / CLDN4.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Properties for Claudin-4 / CLDN4

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~22 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O14493
Immunogen:
Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-4.
GeneID:
1364
Application Western blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200. 
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Background The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer System:
Phosphate buffered saline (PBS), pH 7.2.
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of Claudin 4 protein.
(region surrounding Pro192)
Gene ID 1364
FocusOn and Reviews
Reviews:

Accessory Products

Proteins and/or Positive Controls

Proteins for Claudin-4 / CLDN4 (5 products)

Catalog No. Species Pres. Purity   Source  

Claudin-4 / CLDN4

Claudin-4 / CLDN4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4

Claudin-4 / CLDN4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Claudin-4 / CLDN4

Claudin-4 / CLDN4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Claudin-4 / CLDN4

Claudin-4 / CLDN4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Claudin-4 / CLDN4

Claudin-4 / CLDN4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Claudin-4 / CLDN4 (2 products)

Catalog No. Species Pres. Purity   Source  

Claudin 4 Lysate

Western Blot: Claudin 4 Lysate [NBL1-09246] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for CLDN4.
  Novus Biologicals Inc.

CLDN4 293T Cell Transient Overexpression Lysate(Denatured)

CLDN4 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
  • LinkedIn