NB120-6582 Collagen Type V antibody

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0.1 mg / €420.00

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Rabbit anti Human Collagen Type V


Product Description for Collagen Type V

Rabbit anti Human Collagen Type V.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.

Properties for Collagen Type V

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications C, E, ICC/IF, IP, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Collagen Type V from adult human and bovine tissues
Application ELISA, IHC-Fr, IF, IP, WB
Background This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.
Immunogen affinity purified
Buffer System:
0.01M Na phosphate, 0.25M NaCl, pH7.6, 0.05% Na azide, 0.01% Thimerisol, 15mg/ml BSA
Immunogen affinity purified
Aff - Purified
Cross-reacts with Human and Cow.Expected to cross-react with all Mammals due to sequence homology.Not yet tested in other species.

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