Product Description for Collagen Type VII
Mouse anti Porcine Collagen Type VII LH7.2.
Product is tested for Frozen Sections, Paraffin Sections.
Product is tested for Frozen Sections, Paraffin Sections.
Properties for Collagen Type VII
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | VII |
| Reactivity | Por |
| Applications | C, P |
| Clonality | Monoclonal |
| Clone | LH7.2 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
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|---|---|
| Add. information | Research Areas: Cancer |
| Application | Immunohistochemistry-Frozen, Immunohistology - Frozen; suggested working dilution: 1/5- 1/10., Immunohistochemistry-Frozen |
| Background | Type VII collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa. |
| General Readings | This product has been used in:Kirkham N et al. Type VII collagen antibody LH 7.2 identifies basement membrane characteristics of thin malignant melanomas. J Pathol 157:243-7 (1989). PubMed PMID: 2647941 Heagerty AH et al. Identification of an epidermal basement membrane defect in recessive forms of dystrophic epidermolysis bullosa by LH 7:2 monoclonal antibody: use in diagnosis. Br J Dermatol 115:125-31 (1986). PubMed PMID: 3527251 General / background references:Leigh IM Epithelia 1987:17-29 (0). |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
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Accessory Products
Recommended Secondary Antibodies for Collagen Type VII (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
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Rabbit | AP | C, E, WB | ||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
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Rabbit | Biotin | C, E, WB | ||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
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Rabbit | FITC | E, ICC/IF | ||||
| Acris Antibodies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
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Rabbit | HRP | C, E, WB | ||||
| Acris Antibodies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
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Rabbit | Texas Red | ICC/IF | ||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Rabbit | PE | F | ||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Goat | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
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Goat | Cy2 | |||||
| Acris Antibodies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
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Goat | Cy3 | |||||
| Acris Antibodies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
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Goat | Cy5 | |||||
| Acris Antibodies GmbH | |||||||
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