TA302410 COPS2 / TRIP15 (C-term) antibody

Goat Polyclonal Antibody against ALIEN / TRIP15 / COPS2

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Search for all "COPS2 / TRIP15"

0.1 mg / €360.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Goat anti Bovine, Canine, Human, Mouse, Rat COPS2 / TRIP15

TA302410

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  • TA302410

Product Description for COPS2 / TRIP15

Goat anti Bovine, Canine, Human, Mouse, Rat COPS2 / TRIP15.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for COPS2 / TRIP15

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Alien homolog, COP9 signalosome complex subunit 2, CSN2, JAB1-containing signalosome subunit 2, SGN2, TRIP-15, Thyroid receptor-interacting protein 15
Presentation Aff - Purified
Reactivity Bov, Can, Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Goat
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P61201
Immunogen:
Peptide from C Terminus of the protein sequence according to NP_004227.1; NP_001137359.1.
AA Sequence:
C-LNSLNQAVVSKLA
GeneID:
9318
Property C-term
Application Peptide ELISA: Antibody detection limit dilution 1/16000.
Western blot: 1-3 µg/ml. Approx. 48kDa band observed in Human Brain, Mouse Brain lysates and in lysates of Mouse putuitary cell line NIH3T3 (calculated MW of 51.6kDa according to NP_004227.1).
Immunohistochemistry: 3-5 µg/ml.
In paraffin embedded Human Thyroid Gland shows nclear and cytoplasm staining in activated epithelial cells.
Background TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Concentration 0.5 mg/ml
General Readings 1. Escher N, Kob R, Tenbaum SP, Eisold M, Baniahmad A, von Eggeling F, Melle C.
Various members of the E2F transcription factor family interact in vivo with the corepressor alien.
J Proteome Res. 2007 Mar;6(3):1158-64. PMID: 17330949
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Buffer System:
Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
State:
Liquid purified Ig fraction.
Aff - Purified
Species Reactivity
Species reactivity (expected):
Rat, Canine (Dog) and Cow.
Species reactivity (tested):
Human and Mouse.
Specificity
Specificity:
This antibody detects COPS2/TRIP15 at C-term.

Accessory Products

Proteins and/or Positive Controls

Proteins for COPS2 / TRIP15 (7 products)

Catalog No. Species Pres. Purity   Source  

COPS2 / TRIP15 (transcript variant 1)

COPS2 / TRIP15 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

COPS2 / TRIP15

COPS2 / TRIP15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

COPS2 / TRIP15

COPS2 / TRIP15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

COPS2 / TRIP15

COPS2 / TRIP15 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

COPS2 / TRIP15

COPS2 / TRIP15 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

COPS2 / TRIP15

COPS2 / TRIP15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

COPS2 / TRIP15

COPS2 / TRIP15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for COPS2 / TRIP15 (1 products)

Catalog No. Species Pres. Purity   Source  

COP9 signalosome complex subunit 2 Lysate

Western Blot: COP9 signalosome complex subunit 2 Lysate [NBL1-09380] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for COPS2
  Novus Biologicals Inc.
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