AP05397PU-N Cortisone antibody

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Sheep anti Broad Cortisone


Product Description for Cortisone

Sheep anti Broad Cortisone.
Presentation: Purified

Properties for Cortisone

Product Category Primary Antibodies
Quantity 1 ml
Synonyms 11, 17alpha, 17alpha-Hydroxy-11-dehydrocorticosterone, 20-trione, 21-Dihydroxy-4-pregnene-3, 21-diol-3, 4-Pregnene-17alpha, Kendall's Compound E, Reichstein's Substance Fa
Presentation Purified
Reactivity Br
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Synthetic peptide corresponding to the amino acids 1 - 21 of the native molecule conjugated to Bovine Serum Albumin.
Application ELISA.
Background Cortisone is a hormone. Chemically it is a corticosteroid with formula C21H28O5 and IUPAC name 17-hydroxy-11-dehydrocorticosterone. It is closely related to corticosterone.
Cortisone and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response.
Cortisone is the inactive precursor molecule of the active hormone cortisol. It is activated through hydroxylation of the 11-keto-group by an enzyme called 11-beta-steroid dehydrogenase. The active form cortisol is thus sometimes referred to as hydrocortisone.
Cortisone is sometimes used as a drug to treat a variety of ailments.
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Concentration 17.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Ammonium sulphate precipitation
Buffer System:
Phosphate buffered saline containing 0.09% Sodium Azide (NaN3)
Ig fraction prepared by ammonium sulphate precipitation
Liquid Ig fraction
21-linked antibodies are generally reactive with Cortisone, Cortisol and Prednisolone. The best optimised assay so far evaluated (1/2K FT) gave reactivities of Cortisone (100%), Cortisol (30%) and Prednisolone (10%).

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