AP00332PU-N COX3 antibody

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Rabbit anti Mouse COX3

Product Description for COX3

Rabbit anti Mouse COX3.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for COX3

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms COX-3, Cyclooxygenase 3
Presentation Aff - Purified
Reactivity Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Synthetic peptide mapping to the N-terminus of mouse Cox-3
Add. information Blocking peptide (AP00332CP-N) is available separately.
Application Western Blot: 0.5-4 μg/ml.
Background COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drugs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic activity of COX-1 are primarily involved in the regulation of homeostatic functions throughout the body, whereas PGs formed by COX-2 primarily mediate pain, fever, and inflammation. COX-1 is constitutively expressed, with particularly high expression in gastrointestinal tissues. COX-2 is induced by cytokines and mitogens and is likely to play a role in inflammatory diseases such as rheumatoid arthritis. In rodents and humans, COX-3 encodes proteins with completely different amino acid sequences than COX-1 or COX-2 and without COX activity. It has been suggested COX-3 as the key to unlocking the mystery of the mechanism of action of acetaminophen.
Concentration 0.5 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity purified
Buffer System:
PBS containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
Liquid purified Ig
Aff - Purified
This antibody detects Cox-3.

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