DM360P CREB Binding Protein (CBP) antibody

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Mouse anti Human, Rat CREB Binding Protein (CBP) AC238


Product Description for CREB Binding Protein (CBP)

Mouse anti Human, Rat CREB Binding Protein (CBP) AC238.
Presentation: Purified
Product is tested for Frozen Sections, Paraffin Sections.

Properties for CREB Binding Protein (CBP)

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CREBBP
Presentation Purified
Reactivity Hu, Rt
Applications C, P
Clonality Monoclonal
Clone AC238
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

Purified recombinant CREB-binding protein (CBP)
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application Immunoprecipitation (Not verified)(Ab at 2 micrograms/mg cell lysate). Western Blotting (Not verified). Immunohistology (Formalin/paraffin)(Use Ab at 1-2 micrograms/ml for 30 min at RT). Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
Storage Store the antibody at 4-8°C. Do not freeze. Shelf life: on
Protein Kinase A (PKA) mediated CREB phosphorylation results in the binding of CREB to CBP (CREB-binding protein). Phosphorylation by PKA enables CREB to serve as a scaffold for CBP, which then activates the process responsible for expression of cAMP inducible genes. Sequence analysis of CBP and p300 reveals substantial homology. Reacts with A431 or ML-1 cells and Tonsil.

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