discontinued

AP05645SU-N CRMP2 (C-term) antibody

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0.1 ml / €440.00

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Goat anti Human CRMP2

AP05645SU-N

Product Description for CRMP2

Goat anti Human CRMP2.
Properties: (C-term)
Presentation: Serum
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for CRMP2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms COLLAPSIN RESPONSE MEDIATOR PROTEIN 2
Presentation Serum
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Goat
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide corresponding amino acid sequence 543-557 of human CRMP2.
Property C-term
Application ELISA: 1:10000.
Western Blot: 1:3000; detects bands of approximately 62 and 124kDa in human Alzheimer disease brain cell lysates.
Background CRMP2 is 62 kDa member of the dehydropyrimidinase family. It is involved in axon formation and outgrowth by transporting to axons, the actin cytoskeleton regulating; Rac1-associated protein 1 (Sra-1)/WASP family verprolin-homologous protein 1 (WAVE1) complex. CRMP2 also regulates axon formation and branching by binding tubulin heterodimers thereby enhancing microtubule polymerisation. Through its interaction with ROKalpha, CRMP2 is also thought to play a role in RhoA-dependent signalling. CRMP2 is associated with mesial temporal lobe epilepsy and schizophrenia.
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
General Readings
  1. Kawano, Y. et al. (2005) CRMP2 is involved in kinesin1dependent transport of the Sra1/WAVE1 complex and axon formation. Mol. Cell. Biol. 25:9920 - 9935.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid serum containing 0.09% Sodium Azide (NaN3)
Serum
Specificity
Specificity:
This antibody recognises collapsin response mediator protein 2 (CRMP2), a ubiquitously expressed.
Species:
Human.

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