NB100-947 CTCF Super Novus Pack antibody

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3 vials / €760.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human CTCF Super Novus Pack

NB100-947

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  • NB100-947
  • NB100-947
  • NB100-947

Product Description for CTCF Super Novus Pack

Rabbit anti Human CTCF Super Novus Pack.
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot.

Properties for CTCF Super Novus Pack

Product Category Primary Antibodies
Quantity 3 vials
Presentation Aff - Purified
Reactivity Hu
Applications IP, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
See individual datasheets
Add. information 1 vial each of: NB500-175, NB500-177 and NB500-194.
Research Areas: Cancer
Application immunoprecipitation, Western Blot, Western Blot (NB 500-177), Immunoprecipitation See individual datasheets for dilutions. Other applications have not been tested.
Background We know how important it is to your research to have access to antibodies specific for your model. As it is often impossible to know which antibody will work best for a specific sample and application, we now offer SuperNovus Packs. These packs include different antibodies to the same protein to give you the ability to decide for yourself. The SuperNovus Packs are all offered at a discount price compared to purchasing each antibody individually. The vertebrate insulator protein, CCCTC binding factor (CTCF) is a highly conserved, ubiquitously expressed DNA-binding protein that has widespread capabilities in gene regulation. CTCF contains 11 zinc finger motifs and it is thought that CTCF uses different combinations of zinc fingers to recognise a variety of specific sequences on the DNA to control several important genes. CTCF plays dual roles in cell growth regulatory processes and epigenetic functions. CTCF is a negative regulator of cell proliferation and is located in a region of the chromosome that is frequently deleted in human cancers. The CTCF protein is altered in some breast and prostate tumours. Substitutions from one amino acid to another in the DNA-binding domain change the whole spectrum of the genes regulated by CTCF which can result in cancer development. CTCF was first identified as one of the nuclear factors binding to the regulatory regions of the c-myc gene. Further study of this protein revealed roles in transcriptional repression, insulator function, and imprinting genetic information. Among the multitude of normal CTCF functions, it's involvement in partitioning the genome into active or inactive domains by means of a chromatin insulator function has received particular attention. As an insulator CTCF helps to define the boundaries between the neighbouring genes. Strikingly, all vertebrate chromatin insulators identified so far interact with CTCF.
Storage Store at 4C. Do not freeze.
Format
Purification:
Immunogen affinity purified
Buffer System:
0.09% Sodium Azide
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
These antibodies are specific for human CTCF.
Species:
Human

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