TA347362 Cullin 1 antibody

Rabbit Polyclonal Anti-Cullin 1 Antibody

See related secondary antibodies

Search for all "Cullin 1"

0.1 mg / €335.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse Cullin 1

Product Description for Cullin 1

Rabbit anti Human, Mouse Cullin 1.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Cullin 1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CUL-1, CUL1, Cullin-1
Presentation Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q13616
Immunogen:
The immunogen for anti-Cullin 1 Antibody: A synthesized peptide derived from human Cullin 1.
GeneID:
8454
Application WB: 1:500-1:3000
Background CUL1 Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitition of proteins involved in cell cycle progression, sigl transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functiol specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitition of CTNNB1 and participate in Wnt sigling. SCF(FBXW11) directs ubiquitition of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitition of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5 and probably NFKB2.
Format
Purification:
Affinity-chromatography
Buffer System:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for Cullin 1 (7 products)

Catalog No. Species Pres. Purity   Source  

Cullin 1

Cullin 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Cullin 1 (1-410, His-tag)

Recombinant human CUL1, 1- 410 aa, His-tagged Human Purified > 95 % E. coli
0.25 mg / €750.00
  Acris Antibodies GmbH

Cullin 1 (1-410, His-tag)

Recombinant human CUL1, 1- 410 aa, His-tagged Human Purified > 95 % E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Cullin 1

Cullin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cullin 1

Cullin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cullin 1

Cullin 1 Human Purified
  Novus Biologicals Inc.

Cullin 1

Cullin 1 Human Purified
  Novus Biologicals Inc.

Positive controls for Cullin 1 (1 products)

Catalog No. Species Pres. Purity   Source  

Cullin 1 Lysate

Western Blot: Cullin 1 Lysate [NBL1-09606] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CUL1
  Novus Biologicals Inc.
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