AM00692PU-N CYP2B2 antibody

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Mouse anti Rat CYP2B2 BDI002


Product Description for CYP2B2

Mouse anti Rat CYP2B2 BDI002.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for CYP2B2

Product Category Primary Antibodies
Quantity 10 Blots
Synonyms CYPIIB2, Cytochrome P450 2B2, Cytochrome P450 PB4, Cytochrome P450E
Presentation Purified
Reactivity Rt
Applications E, WB
Clonality Monoclonal
Clone BDI002
Host Mouse
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Rat P450 2B2
Application ELISA.
Western blot (1:100 will yield a strong band with 10 µg of Phenobarbital induced rat microsomes using Alkaline Phosphatase).
Background The Cytochrome P450 superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 to -80°C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Ammonium sulfate precipitation and DEAE chromatography
Buffer System:
PBS, pH 7.4
Liquid Ig fraction
This antibody is specific for Cytochrome P450 (2B1, 2B2).
Cross reacts weakly with P450 2A1.
Gene ID 361523

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